I'm running a game in the Points of Light setting, and was able to adapt Khyber's Harvest with minimal effort. I centered the cult around Torog, the evil deity of torture and imprisonment from the default 4E setting. A little bit of reskinning, change an NPC's race (orcs aren't generally peaceful outside of the Eberron setting), and add appropriate foreshadowing involving a cult of the "God That Crawls," and I had myself a fun adventure.
I ran this adventure early in my group's campaign. They were still getting used to the mechanics of a tabletop RPG (these were all newcomers to the hobby). I found Khyber's Harvest to be appropriate for my group. It was darker than my previous adventure, highlighting that D&D is capable of supporting multiple sub-genres. It was pretty straightforward, but had a nice skill challenge early on. The skill challenge was well through out, in that it didn't actually feel like a skill challenge. My players simply told me what their PCs were doing during an investigation, made some appropriate dice rolls, and I kept track of successes and failures. They passed the skill challenge, but if they'd failed, the adventure describes how the PCs "fail forward" (to borrow a term from 13th Age), progressing the story, but causing a setback.
Being a free download, you certainly can't beat the price. I recommend that you give it a try if you're interested in a low-level D&D adventure that's not your run-of-the-mill goblin/kobold-slaying fest.